Cloud Technologies for Microsoft Computational Biology Tools

Cloud Technologies for Microsoft Computational Biology Tools

Executing large number of self-regulating tasks or tasks that execute minimal inter-task communication in analogous is a common requirement in many domains. In this paper, we present our knowledge in applying two new Microsoft technologies Dryad and Azure to three bioinformatics applications. We also contrast with traditional MPI and Apache Hadoop MapReduce completion in one example. The applic...

Degenerate Primer Design Using Computational Tools Computational Molecular Biology

The polymerase chain reaction (PCR) is widely used to uncover new information about genes and genomes, but is limited in that it is highly dependent on the use of specific and sensitive primers to yield good results. Primers can target a specific, known sequence, but what is often more interesting is the use of degenerate primers to target unknown sequences. Degenerate primers are designed base...

Virtual Cell: computational tools for modeling in cell biology.

The Virtual Cell (VCell) is a general computational framework for modeling physicochemical and electrophysiological processes in living cells. Developed by the National Resource for Cell Analysis and Modeling at the University of Connecticut Health Center, it provides automated tools for simulating a wide range of cellular phenomena in space and time, both deterministically and stochastically. ...

Computational Modeling, Formal Analysis, and Tools for Systems Biology

As the amount of biological data in the public domain grows, so does the range of modeling and analysis techniques employed in systems biology. In recent years, a number of theoretical computer science developments have enabled modeling methodology to keep pace. The growing interest in systems biology in executable models and their analysis has necessitated the borrowing of terms and methods fr...

New Microsoft Component Technologies